Top 15 sedatives for adults

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The best means of synthetic origin

1 Afobazole The optimal combination of efficiency and safety
2 Valoserdin Better economy
3 Valemidin The best remedy with a combined action
4 Tryptophan Formula of Calm Popular drug with a mixed reputation

The best vegetable based products

1 Novo-Passit The best agent with anxiolytic (anti-anxiety) action
2 Persen The best natural sleeping pills
3 Motherwort Forte Evalar Mild sedative + tonic
4 Positive Multicomponent herbal complex to support the nervous system

The best homeopathic remedies

1 Tenoten The best homeopathic sedative
2 Rescue Remedy Spray "Ambulance" under stress. The most convenient way to use
3 Homeostres Effective sedative, but contraindications
4 Calm Pills The most affordable sedative homeopathic for adults

Top Soothing Herbal Fees

1 Tea drink Enerwood Valery The best combination of pleasant taste and benefits to the body.
2 Phyto sedan Excellent herbal remedy in the complex therapy
3 Herbal tea "Soothing with melissa" Inexpensive natural wide-range herbal medicine

At the end of the last century there was a saying, stress, a disease of the 20th century. Century 21 has arrived, but nothing has changed. As before, “all diseases from nerves”: the rhythm of life is accelerating, demands are getting higher, fatigue is increasing. Pharmacology also does not stand still, offering new and new sedatives. To help you understand this diversity, we offer our rating of sedatives. Only OTC products are involved in the rating.

It is necessary to know that most of the sedative drugs "go to the maximum" one to two weeks after the start of treatment. Therefore, it is not necessary to rush and exceed the dosage specified in the instructions, even if at first it seems that the medicine “does not work”.

There are contraindications. Check with your doctor.

The best means of synthetic origin

No matter how many prejudices against "chemistry", everything that happens inside the body, by and large only a complex of chemical reactions and physical interactions. And the more scientists learn about these reactions and interactions, the more accurately and precisely the drugs work. In this section, we have included both the achievements of pharmaceutical synthesis, and the drugs that could be called natural, without adding a synthetic substance to them to enhance the effect.

4 Tryptophan Formula of Calm


Popular drug with a mixed reputation
A country: Russia
Average price: 254 rub.
Rating (2019): 4.5

We begin our review with Russian-made capsules Tryptophan Formula of Tranquility from the brand Evalar. The unique mechanism of action of the amino acid, which gave the name of the drug, allows it to fully affect the human body both day and night, contributing to the normalization of the psycho-emotional background and improve sleep quality. Strengthened with vitamins B5 and B6, L-tryptophan helps to quickly deal with nervousness, reduces aggressiveness and irritability, and also reduces the adaptation period during a time zone change. For best results, this tool is recommended to take 1 capsule twice a day for 1 month. If necessary, after a short break, the course can be repeated (after consultation with the doctor).

In their reviews, many users note the good effects of the drug, but there are also those who have not felt the expected effect at all.Because of such ambiguous assessments, we leave “Tryptophan Formula of Calmness” in the last place in its category of the best sedatives.

3 Valemidin


The best remedy with a combined action
A country: Russia
Average price: 115 rub.
Rating (2019): 4.6

Another drug that could be called a plant, if it was not added diphenhydramine as a sedative component. However, its dosage is such that only to potentiate the action of herbal extracts. In addition to valerian and mint, known for its soothing properties, the remedy contains motherwort and hawthorn extracts, which reduce blood pressure. We would not advise replacing antihypertensive drugs with hypertensive experience with this drug, but it may help relatively young people who notice elevated pressure during stress (previously this condition was called neurocirculatory dystonia or cardiovascular dystonia). In addition, both hawthorn and mint relieve spasms of the smooth muscles of the gastrointestinal tract, so this remedy may be the best for those who suffer from a “bearish disease” or simply feel discomfort in the stomach.

Contraindicated in pregnancy, during breastfeeding, up to 18 years, hypotensive (can even lower blood pressure).

2 Valoserdin


Better economy
A country: Russia
Average price: 75 rub.
Rating (2019): 4.7

This composition has been around for many years, and our grandmothers have used it. Ethyl bromizovalerianic acid ethyl ester, peppermint oil and oregano dissolved in alcohol. Phenobarbital, a known sleeping pill, is added at a dosage lower than therapeutic, but sufficient to potentiate the action of herbal sedatives. With proper use in doses not exceeding the stipulated instructions (from 15 to 30 drops no more than 3 times a day), the drug is not addictive. Nevertheless, phenobarbital in its composition enhances the action not only of plant extracts, but also of any sedatives and reduces the effect of tonic ones. In addition, it reduces the effects of antibiotics and contraceptives. Contraindicated in pregnancy, during feeding, up to 18 years. In general, valoserdin is an inexpensive, fairly effective, despite its venerable age, and a fairly safe means, based on the totality of merit, which has won a place in our rating.

Signs of depression: if you find yourself with 5 or more of the symptoms from the following list, which do not go through 2 or more weeks - see a doctor immediately!

  • bad mood;
  • altered sleep: intermittent, restless, with early awakening;
  • hobbies disappeared, previously interesting things became uninteresting;
  • difficult to concentrate;
  • difficult to choose from several options to make a decision;
  • lethargy, lethargy;
  • constant guilt, selflessness;
  • difficult to stir, apathy;
  • change in appetite: loss of desire to eat or constant “zhor”

1 Afobazole


The optimal combination of efficiency and safety
A country: Russia
Average price: 378 rub.
Rating (2019): 4.8

It soothes, reduces anxiety, normalizes the neuro-psychological state when trying to quit smoking or “quit” with alcohol, during PMS. Improves sleep, if problems with falling asleep are caused by unpleasant thoughts. It is combined with alcoholic beverages, which allows not to attract too much attention on family and friendly holidays. It can not be taken during pregnancy, breastfeeding and up to 18 years. Due to the fact that as an auxiliary component (filler) tablets contain lactose, people who are intolerant of this substance cannot be used. In general, this is an extremely small list of contraindications for a sedative, therefore, for the combination of efficacy and safety, Afobazol takes a worthy place in our rating.

The best vegetable based products

No matter how effective modern pharmacology may be, there are quite a few admirers of traditional herbal remedies.This has its own logic: the effect of herbal remedies, as a rule, is milder, often such funds have a wider age range and a smaller list of possible side effects. Nevertheless, it must be remembered that herbal remedies are more allergenic than synthetic: herbs never contain only one active ingredient, and the more complex the composition, the higher the probability of allergies. Herbal medicine is in principle contraindicated for people suffering from any allergic pathology, ranging from hay fever to bronchial asthma. Many, of course, ignore this rule, and undesirable consequences do not always occur, but we must warn.

4 Positive


Multicomponent herbal complex to support the nervous system
A country: Russia
Average price: 660 rub.
Rating (2019): 4.5

Natural plant complex "Positive" is designed to stabilize the nervous system in conditions of high psycho-emotional stress. It helps to keep calm in especially difficult situations, eliminates the feeling of unreasonable anxiety, improves night sleep and mood during the day. The product contains a number of effective natural extracts - ginseng root, prickly Eleutherococcus and Ginkgo biloba, which have mild antidepressant and tonic properties.

“Positive” is produced in the form of small gelatin capsules, which should be taken in the morning with meals. The course of treatment is at least 14 days. A second course is possible after a 1-2 month break. There are no strict contraindications for taking dietary supplements, however, in case of serious pathologies of the cardiovascular system, elevated blood pressure or when the child is waiting, it is better to refuse to use this drug.

3 Motherwort Forte Evalar


Mild sedative + tonic
A country: Russia
Average price: 291 rub.
Rating (2019): 4.6

One of the most popular and time-tested natural soothing preparation based on motherwort extract has not only a sedative, but also a tonic effect on the body. One tablet of Motherwort Forte from the company Evalar contains in its composition a daily dose of magnesium carbonate and vitamin B6, which helps to quickly remove the feeling of emotional tension, removes anxiety and irritability. In addition, the drug contributes to a mild decrease in blood pressure, strengthens the heart muscle and acts as a delicate muscle relaxant. The undoubted "plus" of the remedy is that it is not addictive, even with a long period of therapy.

The recommended dosage (if your doctor did not prescribe another appointment) is 1-2 tables. per day taken with meals. Contraindications include pregnancy, peptic ulcer and 12 duodenal ulcers, as well as erosive gastritis in the acute stage. Sold without a prescription.

2 Persen


The best natural sleeping pills
A country: Slovenia
Average price: 360 rub.
Rating (2019): 4.7

The composition of this tool is traditional and simple: extract of valerian, lemon balm and peppermint. However, this combination, judging by the reviews, is very effective as a sleeping pill. But it is necessary to use it during the day with caution, especially if you are driving a car: such side effects as lethargy and lethargy are possible, typical, however, for any valerian-based product. However, in adults, the choice of sedatives that do not affect the reaction is quite large, but the fact that the drug can be used in children from the age of three is a definite plus of this medicine, making it the best in its category.

1 Novo-Passit


The best agent with anxiolytic (anti-anxiety) action
A country: Czech
Average price: 206 rub.
Rating (2019): 4.8

It would seem that this means a place among synthetic drugs due to the presence of guaifenesin in it.Like Dimedrol, developed as an antiallergic agent, and now used mainly as a sedative or sedative, guaifenesin was patented in 1012 as an antitussive drug, and is now used as anxiety remedy. However, the substance is of natural origin and is extracted from the bark of the guaiac tree, which allowed Novopassit to take a place in the ranking as the best herbal preparation with an anxiolytic effect. Because its main components are entirely natural: rhizomes and roots of valerian, lemon balm, St. John's wort, hawthorn, passionflower, hops, elder. Of contraindications - age up to 12 years, allergic to the components of the drug. Relative contraindication - pregnancy.


The best homeopathic remedies

Official science considers homeopathy ineffective - a recent verdict of the commission of the Russian Academy of Sciences recognized it as false science. Nevertheless, these funds also have their fans, which prompted us to single out the most famous of the homeopathic sedative drugs in a separate section of the rating. Without discussing the issues of effectiveness, we can say that, at least, the homeopathic medicine cannot do any harm.

4 Calm Pills


The most affordable sedative homeopathic for adults
A country: Russia
Average price: 81 rub.
Rating (2019): 4.5

Sedative remedy for adults with the “speaking” name “Calm” is produced in the form of sublingual tablets that can be consumed without drinking water. This low-cost homeopreparation is prescribed for increased excitability of the central nervous system, irritability, insomnia, frequent migraines, as well as neuroses associated with cardiovascular disorders. Not addictive. Take "Calm" should be in the morning, a quarter of an hour before breakfast, without chewing and swallowing. Daily dose - 1 tablet for 1-2 months. In stressful situations, it is recommended to make reception more frequent, but not more than 3 times a day.

This drug can not be used to treat children under the age of 18 years. It is also contraindicated for pregnant and lactating women. Patients with congenital lactase deficiency - with caution. The average price for homeopathic pills “Calm” does not exceed 90 rubles, which allows us to call this tool the best in accessibility in its category.

3 Homeostres


Effective sedative, but contraindications
A country: France
Average price: 373 rub.
Rating (2019): 4.6

French homeostres pills based on belladonna grass and Klobuchkov’s fighter (also known as “wolf root”) are a multi-component homeopathic remedy for anxiety, irritability and insomnia. The tool has a fairly strong effect on the nervous system, so it has a limited duration of reception - not more than one week. The maximum daily rate is 6 tab., Which is recommended to slowly dissolve in the mouth for 2 pieces. three times a day.

It should be noted that the composition, in addition to the active substances, includes lactose and sucrose. Therefore, people with elevated blood sugar levels (diabetics of the 1st and 2nd type), as well as those who have been diagnosed with hypolactasia, should use Homeostres with extreme caution. The drug is prescribed only for adult patients. It is contraindicated in children, pregnant and lactating women.

2 Rescue Remedy Spray


"Ambulance" under stress. The most convenient way to use
A country: Great Britain
Average price: 1293 rub.
Rating (2019): 4.7

The action of the homeopathic means of production of the British pharmaceutical company A.Nelson & Co.Limited is based on Bach's flower homeopathy, a direction of unconventional therapy that assists the body in nervous overstrain. In Russia, brand products have been registered with the Ministry of Health, therefore their use is officially allowed.

Due to its non-standard form of release, Reskyu Remedi sublingual spray has the fastest action, which is especially important for restoring the emotional background in stressful situations. Available in bottles of 10 and 20 ml. The recommended daily intake is at least 4 pshik per day. The composition includes grape alcohol, so the spray is contraindicated in children up to 3 years. There was no specific effect of low doses of the drug on drivers or workers in other areas requiring increased attention. In the opinion of users, Rescue Remedy is an effective ambulance that can save our nervous system in moments of difficult circumstances.


1 Tenoten


The best homeopathic sedative
A country: Russia
Average price: 217 rub.
Rating (2019): 4.8

According to the instructions, the drug has antidepressant, antiasthenic (reduces fatigue) and anxiolytic (anti-anxiety) effects. Also, according to the manufacturer, the tool strengthens the central nervous system, improves attention and memory and increases the body's resistance to stress. Approved for use in children from 3 years.

Top Soothing Herbal Fees

Using herbal remedies to relieve feelings of tension, anxiety and sleep problems is one of the most ancient ways to strengthen “shattered” nerves. Despite the fact that these drinks are completely natural and contain only plant extracts, it should be remembered that if overdose, they can cause serious pathologies requiring urgent hospitalization. Therefore, before taking any soothing herbal tea, be sure to consult with your doctor in order not to cause even greater harm to your health.

3 Herbal tea "Soothing with melissa"


Inexpensive natural wide-range herbal medicine
A country: Russia
Average price: 152 rub.
Rating (2019): 4.6

Since ancient times, Melissa has been considered one of the most effective plants for treating various pathologies of the nervous system. Tea with this aromatic weed has a mild sedative effect, as well as relieves muscle spasms (for example, during critical days in women). Herbal infusion with melissa is indicated for men with erectile dysfunction, its proper use has a beneficial effect on reproductive function and reduces increased sexual excitability.

In addition to the main component of the plant includes mint leaves, motherwort, hop fruit, valerian root, rose hips and hawthorn. There are practically no contraindications for this herbal preparation, but it should be used with caution by people with a tendency to allergic reactions to herbs. “Herbal tea with melissa” is sold as dry raw material in bags of 75 g. To prepare one serving, 1 table is enough. spoons of crushed plants, brewed a glass of boiling water.

2 Phyto sedan


Excellent herbal remedy in the complex therapy
A country: Russia
Average price: 76 rub.
Rating (2019): 4.7

Soothing collection "Fitosedan" is available in disposable filter bags, which should be brewed with boiling water and drink half a cup twice a day before meals. The drug is recommended to take a course of 2-4 weeks, if necessary, re-treatment requires consultation with the doctor. The composition of the natural remedy includes motherwort grass (almost half of the total volume), 20% hop cones, 15% peppermint leaves and the same amount of valerian root. All these medicinal plants are distinguished by their ability to reduce the excitability of the central nervous system; they have a moderate soothing and spasmolytic effect.

Being a part of complex therapy, the collection helps to effectively deal with increased irritability and neurosis.However, with long-term intake and non-compliance with dosages, "Fitosedan" can provoke a decrease in psychomotor reactions and a loss of concentration, which should be taken into account by those who spend a lot of time driving.


1 Tea drink Enerwood Valery


The best combination of pleasant taste and benefits to the body.
A country: Russia
Average price: 330 rub.
Rating (2019): 4.8

Enerwood teas and natural drinks are well known to many healthy lifestyles and those who prefer to maintain good health with the help of “gifts of nature”. Soothing tea drink Valery optimally combines taste and benefit. It consists of herbs that have long been known for their mild sedative effect - motherwort and chamomile, and thanks to additives in the form of cinnamon and pieces of dried apples, tea acquires an incredibly pleasant and bright aroma. The raw materials that underlie this herbal remedy are ecologically safe and have a high concentration of beneficial substances, since they were collected at the peak of their biological activity.

According to reviews, Valery tea contributes to a more sound sleep, relieves nervous tension, and also helps to maintain the adequacy and peace of mind in stressful situations (for example, during checks at work or exams at an educational institution). For the manifestation of the maximum effect, the course of taking the plant should be from 10 days to 2 months.

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Attention! The above information is not a guide to your purchase. For any advice should contact the experts!

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14 comments
  1. Valya
    All life is one continuous stress, until you get to work, you are all nervous. And in the evening after work in general the pipe, barely falling asleep from stress.
  2. Anastasia
    Exactly, until you reach it, while you collect the weight of the cork, you are late, all on nerves. And there are always some problems at work. I felt the result for 4-5 days. I like it. And it’s still available and contains vitamins for deep sedation and strengthening of the nervous system.
  3. Ala
    I was very worried when my daughter had to go to the first class, of course this anxiety was reflected in her, she also became nervous, irritable, tearful. We helped herbal teas at night and baby formula bears calm. There are no problems at school;
  4. Olga
    I took tenoten after a protracted depression. He “pulled” me out of it literally in a couple of months! Very good drug turned out

    Tenoten is the best remedy for me. Literally pulled me out of a lingering depression. For a couple of months for sure.
  5. Irina
    Of all the sedatives, tenoten helped me the best. He concentrates attention, and increases working capacity, plus gives him the necessary peace for the soul.
  6. Lana
    I like natural products without chemistry supposedly motherwort. But I myself drank and sometimes I drink the formula of tranquility for the prevention of tryptophan, I slept badly at night, I could not sleep during the day. As a result, she got nervous stress and apathy to everything. Saw 1 month tryptophan, sleep improved. By the way, Donormil also dabbled, helped better than phenizipam or dimidrol, although it is sold without a prescription at the pharmacy.
  7. Anna
    Best of all listed in this article is tenoten. Because it acts not only as a sedative, but also perfectly improves the performance of the head. You start thinking better and think in general. Remarkable tool. I highly recommend it to everyone
  8. Lesya
    And I really like glycine with my action, but I prefer glycine forte - there is more dosage in it and I also have vitamins for the brain. It gradually and very gently improves the functioning of the nervous system, normalizes sleep and improves brain function. I always drink it under loads at work or in stressful situations. It helps me a lot.
  9. Anna
    I like the most soothing tenothenes. I literally feel the effect of it immediately after taking it, plus there are no unpleasant side effects from it
  10. Katerina
    For a long time trying to find a good soothing daughter (5 years). She began to worry strongly, became scattered, and so on. She asked her friends if they had such a thing, and if so, what they gave to the children. In most cases, I heard "baby formula bears calm," decided to stop on it and bought it. The composition is natural, the price is acceptable; gave 1 tablet per day with food for about 2 months.
  11. Den
    Afobazole is homeopathy! It generally must be removed!
  12. Natasha
    I used to calm down saw melissa and mint, but now, unfortunately, these herbs stopped helping me at all, so I learned from a friend about motherwort forte, which rather quickly helped me to improve my emotional state, even though I had a favorable influence on my sleep, It became much faster in the evenings to fall asleep, and not try in the middle of the night The price suits them completely, because they are absolutely not expensive, especially if you take them to the shop. Evalar, there are always some discounts
  13. Galina
    I would not include valoserdin in this list, what's the point of it being cheap, if you can't take it? The smell is disgusting, the dropper drops as it were, then it drips. If we are to look at such strong medicines, then it is better to take valokardin. The composition is identical, but at least for people made.
  14. Irina
    It is strange that Vitango did not mention. Only these pills help me to cope with stress and external irritants. Enough week course to bring the nerves in order.

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