15 best drugs for the liver

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The best hepatoprotectors based on essential phospholipids

1 Essentiale Forte N Bestseller. Double action
2 Phosphogliv Anti-inflammatory activity. A complex approach
3 Essliver Forte Enriched composition (6 vitamins). Quick help
4 Resalut Pro Oxygen free technology. Cholesterol-lowering effect

The best hepatoprotectors of plant and animal origin

1 Hofitol Best for toxicosis during pregnancy. Minimum contraindications
2 Liv-52 Popular herbal remedies. For adults and children from 6 years
3 Karsil The best supporting tool. Small percentage of adverse reactions
4 Cholenyme Combined hepatoprotector. The lowest price

Top hepatoprotectors of synthetic origin

1 Ursofalk The best release form (suspension). For the smallest (0+)
2 Urdoksa The best Russian analogue. Immunomodulatory effects
3 Ursosan Costly medicine. Tablets and capsules

The best amino acid hepatoprotectors

1 Heptral High efficiency. Antidepressant activity
2 Heptor Best for prevention. Normalization of digestion

The best vitamin-like hepatoprotective agents

1 Hepatrine Detoxification. Sachets
2 Ovesol Choleretic effect. Filter bags

Under the hepatoprotectors imply a group of drugs intended primarily to stimulate the regenerative process of the structural cells of the liver parenchyma (hepatocytes). Another function assigned to this kind of medicine is to protect the liver from various negative effects, be it poisons and toxins, alcohol, "chemistry", smoked and fatty foods, and so on.

Until now, there is no recognized classification of drugs-hepatoprotectors in medicine. Most often, drugs are divided into groups according to:

  1. With origin (natural, synthetic);
  2. With chemical composition (phospholipids, amino acids, vitamins);
  3. With mode of action (choleretic, antioxidant, etc.).

We have compiled a ranking of the best hepatoprotective agents for you to make it easier for you to make a choice. Please note that some of the listed drugs are not dispensed from the pharmacy without a prescription.

There are contraindications. Check with your doctor.

The best hepatoprotectors based on essential phospholipids

Reception of hepatoprotectors of this group provides restoration of the membrane of liver cells on the principle of embedding essential phospholipids in it. The feature presented in the category of drugs is minimized risk of side effects.

4 Resalut Pro


Oxygen free technology. Cholesterol-lowering effect
A country: Germany
Average price: 454 rub.
Rating (2019): 4.6

The drug Rezalut Pro on the basis of soybean phospholipid extract is considered, along with other nominees of the rating, as an effective hepatoprotector for restoring liver cells and improving the flow of bile. The peculiarity of the product is a unique oxygen-free technology, which allows to preserve the active substance without the addition of dyes and other "chemicals": the output is "pure" phospholipids, enclosed in a vacuum shell. Among the indications for the medication are chronic hepatitis, cirrhosis, stetohepatosis and toxic liver damage.

The result of taking a hepatoprotector is to normalize lipid metabolism by reducing cholesterol. Users share observations in observations that at the end of the course they managed to eliminate many discomfort in the liver area - food became better digested, heartburn and stagnation in the gastrointestinal tract disappeared, pain sensations stopped bothering.In addition, capsules have proven themselves for preventive purposes, for example, during exacerbations or holidays, when tables traditionally crack from an abundance of junk food and alcohol.

3 Essliver Forte


Enriched composition (6 vitamins). Quick help
A country: India
Average price: 304 rub.
Rating (2019): 4.6

The Essliver Forte hepatoprotector is an affordable equivalent of more expensive drugs. The ridge of this product is a composition enriched with 6 vitamins (E, B1, B2, B3, B6, B12) and a compound led by essential phospholipids. The combined drug (multivitamins + phospholipids) boasts hepatoprotective, lipid-lowering and hypoglycemic properties.

The drug in a short time restores the function of the liver and increases its detoxification role in case of cell damage due to various reasons. Users in the reviews note that the tool helps well when problems with the gastrointestinal tract, which instantly affect the overall health, condition of the skin, hair and nails. Capsules, despite their considerable size, are ingested easily. Attention when reading the instructions deserve side effects, which, unlike most of the funds, are practically absent (allergies and possible epigastric discomfort).

2 Phosphogliv


Anti-inflammatory activity. A complex approach
A country: Russia
Average price: 444 rub.
Rating (2019): 4.7

The drug "Phosphogliv" in 2001 was awarded the nomination "Discovery of the Year" of the All-Russian pharmaceutical competition "Platinum Ounce." Since then, the agent has been a frequenter in the top of the most effective hepatoprotectors based on essential phospholipids. Doctors recommend it as antiviral, hepatoprotective and membrane stabilizing: gelatin capsules are indicated for adults and children over 12 years old for prevention (poor ecology, stress, poor nutrition), recovery (overeating, alcohol and drug intoxication) and treatment (hepatosis, hepatitis, steatosis) the liver.

This is the only hepatoprotector, according to the state register, containing glycyrrhizic acid in its composition. The reviews emphasize that this is a relatively inexpensive Russian-made hepatoprotector with anti-inflammatory activity. The regimen implies the use of 1-2 capsules three times a day during the meal course on average for 3 months. Upon completion of the course, you can safely rely on the restoration of liver cells, the normalization of protein and lipid metabolism, improving the elasticity of the body.


1 Essentiale Forte N


Bestseller. Double action
A country: France
Average price: 558 rub.
Rating (2019): 4.8

Essentiale Forte N is one of the most popular hepatoprotectors. If you are familiar with symptoms such as fatigue, loss of appetite and heaviness in the right hypochondrium, you should look at this tool. The drug helps to restore liver cells, which in turn has a positive effect on improving metabolism and the work of the whole organism. The peculiarity of the drug is a double effect: the drug is involved both in the active regeneration of hepatocytes and in their protection by providing an antioxidant effect. More than 200 clinical studies have confirmed: "This is an effective and safe drug."

Hepatoprotector goes on sale in the form of gelatin capsules of 30, 90 and 100 pieces per pack. It is released from the pharmacy without a prescription. During the day, take 2 capsules during breakfast, lunch and dinner. Thus, the daily dosage is 6 capsules, and this moment causes outrage among a number of users. From the positive in the reviews mention the rapid improvement after poisoning, the pleasant smell of capsules, a small percentage of side effects. Many pregnant women shared that the medicine helped them to relieve symptoms of toxicosis.

The best hepatoprotectors of plant and animal origin

The peculiarity of such hepatoprotectors lies in their ability to accelerate the recovery of liver cells during the treatment of cirrhosis, hepatitis, alcohol damage, liver failure and other organ pathologies.

4 Cholenyme


Combined hepatoprotector. The lowest price
A country: Belarus
Average price: 134 rub.
Rating (2019): 4.5

The hepatoprotector of the Belarusian manufacturer “Holenim” becomes the winner in the “Best Price” nomination. Experts recommend this combined animal product for the treatment of liver diseases and functional disorders of the gastrointestinal tract, as well as a powerful drug support.

The tool has a pronounced cholekinetic action, helps to improve the functional state of the gastrointestinal tract and the normalization of the process of assimilation of food. The reviews confirm that the hepatoprotector improves the functioning of the digestive system, eliminates bile stasis, bitterness and dry mouth, relieves pain in the area of ​​epigastrium. Swallowing tablets does not cause difficulties, allergic reactions rarely occur.

3 Karsil


The best supporting tool. Small percentage of adverse reactions
A country: Bulgaria
Average price: 347 rub.
Rating (2019): 4.5

Means of plant origin "Kars" based on the extract of thistled milk Thistle (silymarin). This component supports the liver, promotes cell repair, reliably protects against toxic substances and free radicals. The indications for treatment of the drug with hepatoprotective and antioxidant effects are toxic lesions and chronic inflammatory diseases of the liver. However, the prophylactic orientation brought the greatest popularity to the hepatoprotector.

The drug goes on sale in the form of pills, which is a big plus, judging by the reviews. Users emphasize that pills are easily swallowed without leaving an unpleasant aftertaste. Can not but rejoice and a small percentage of side effects. Most of the remedies are prescribed as a supportive measure during or after the course of antibiotics. Also, the drug is considered a good sorbent, which comes to the aid of poisoning and intestinal disorders. The price is not cheap, but acceptable.

2 Liv-52


Popular herbal remedies. For adults and children from 6 years
A country: India
Average price: 298 rub.
Rating (2019): 4.6

Liv-52 has been produced in India since 1955. This is a combination product of plant origin, which has an antitoxic, hepatoprotective, cholekinetic and antioxidant action. The high efficiency of herbal remedies in relation to liver pathologies is due to well-chosen components of the composition (prickly capers, chicory, black nightshade, etc.). The medicine helps to regenerate liver cells, strengthen intracellular metabolism, prevent the formation of gallstones and improve its contractile function.

Hepatoprotector is in stable demand in pharmacies. In the reviews are divided - "Do not expect a quick effect, because it is grass!". Upon completion of the jar (an average of 17 days of intake), there is a surge of energy, cholesterol returns to normal, and digestion of food is no longer accompanied by discomfort. Slowly but surely, liver cells are restored.

1 Hofitol


Best for toxicosis during pregnancy. Minimum contraindications
A country: France
Average price: 344 rub.
Rating (2019): 4.7

Hepatoprotector "Hofitol" is characterized by a pronounced choleretic effect. The pledge of the effectiveness of the drug - a well-chosen set of active substances. Carotene, riboflavin, thiamine, ascorbic acid and inulin, which are part of the leaves of the field artichoke, are responsible for the normalization of metabolic processes in the body. The tool is also famous for its extensive antioxidant and anti-toxic effect, and thus has a positive effect on the protection and restoration of liver cells.

Herbal tablets "Hofitol" - one of the most frequently prescribed remedies for toxicosis.The instructions say that pregnancy and lactation are not a contraindication, but the reception of this hepatoprotector is possible exclusively under the supervision of a physician. With a mild toxicosis, the effect is felt almost instantly, with a stronger degree, on the third or fourth day of administration. Such advantages of the drug as vegetable origin, democratic cost and minimum contraindications darken the high consumption of tablets - 2-3 pieces. three times a day.


Top hepatoprotectors of synthetic origin

The most effective hepatoprotectors today are considered drugs for the treatment and prevention of liver pathologies of synthetic origin. Ursodeoxycholic acid, which is a part of them, helps to intensify the output of bile, lower cholesterol, and improve pancreatic and gastric secretion. Most importantly, there is no age limit for this active substance. Such drugs are safe even for the smallest.

3 Ursosan


Costly medicine. Tablets and capsules
A country: Czech
Average price: 872 rub.
Rating (2019): 4.7

The manufacturer offers hepatoprotector "Ursosan" in tablets and capsules. The latter are most in demand, as reviews show. This drug is mainly used by adults and children over 3 years old. The medicine helps well in cleansing the liver of toxins and toxic substances, getting rid of bitter taste in the mouth and relieving pain syndromes. In addition, it is an effective tool for serious diseases such as hepatitis of various origins, cholelithiasis, hepatosis, etc.

Users emphasize that the agent acts on hepatocytes during a long course of treatment, as a rule, the result becomes replaced after 3 months of administration. So wait an instant result is not worth it. Due to the duration of the drug intake and the consumption of capsules (2-3 capsules per day), the hepatoprotector substantially beats the pocket.

2 Urdoksa


The best Russian analogue. Immunomodulatory effects
A country: Russia
Average price: 772 rub.
Rating (2019): 4.8

Hepatoprotective agent "Urdoksa" is famous for its immunomodulatory, cholekinetic, cholelitholytic, hypolipidemic and hypocholesterolemic effect. The list of indications for treatment of the drug indicates various pathologies of the liver and gallbladder (cirrhosis, stones, reflux gastritis, biliary dyskinesia, etc.). When you read the instructions, the duration of therapy is noticeable - from six months to a year.

In the reviews, the remedy is referred to as the cheaper analogue of Ursosan, noting that this hepatoprotector is in no way inferior to the latter in effectiveness. The first results make themselves felt somewhere after the month: pains in hypochondria disappear, dry mouth disappears, stool normalizes. Medium-sized capsules are unstable, so swallowing is quite simple. Side effects are practically not observed.


1 Ursofalk


The best release form (suspension). For the smallest (0+)
A country: Germany
Average price: 1 120 rub.
Rating (2019): 4.9

The peculiarity of the hepatoprotector for the normalization of liver function "Ursofalk" - the release of the drug in the form of a suspension for oral administration. This form is preferred for children under 3 years based on ease of use. For older children and adults, the manufacturer also provides the drug in tablets and capsules. As for the suspension, users emphasize that it has a pleasant lemon flavor, so babies rarely strive to spit it out. The measuring cup in the set makes dosing easier.

Unanimously to the shortcomings, judging by the reviews, include a large amount. It is possible to store an opened bottle for only 4 months, and the treatment does not require all 250 ml of the composition, and sometimes nothing is needed, for example, 50 ml. Thus, part of the tool remains unclaimed. But the advantages of the drug overlap with more than such a blemish as the absence of a small bottle of small volume, and high cost. The drug quickly leads to normal blood counts, in particular, helps with jaundice, quickly lowering bilirubin.

The best amino acid hepatoprotectors

Drugs from this category are recommended for those who have experienced severe liver damage. Please note that the main active substance of this kind of funds (ademetionin) provides the likelihood of a large number of negative side reactions. For this reason, amino acid hapatoprotectors are prescribed extremely rarely.

2 Heptor


Best for prevention. Normalization of digestion
A country: Russia
Average price: 1 029 rub.
Rating (2019): 4.8

"Heptor", as well as other drugs from the category of amino acid hepatoprotectors, has antidepressant activity, choleretic and cholekinetic action. The indications for taking this medication are hepatitis of various origins, intrahepatic cholestasis, cirrhosis, and a number of other pathologies associated with the work of the organ. It is an excellent medicine for removing harmful substances from liver cells, protecting and preventing hepatic dysfunction.

In the absence of symptoms of "depressed" liver, two tablets per day are enough. Thus, two packs of 20 pieces each will be enough for a 20-day preventive course of administration. For the treatment of specific pathologies of the liver for the exact dosage and duration of the course will have to consult a doctor, as this is a purely individual moment. As for side effects, in the reviews they note that during the first week such troubles as nausea and diarrhea are often observed, apparently, these symptoms are accompanied by intensive cleaning of the liver. However, soon the discomfort is replaced by the first positive results - energy appears, the mood rises, the weight in the side goes away, the appetite improves.


1 Heptral


High efficiency. Antidepressant activity
A country: Italy
Average price: 1 590 rub.
Rating (2019): 4.9

The hepatoprotector “Heptral” is distinguished by its antidepressant activity. Among the directions of the drug are also neuroprotective, choleretic, antioxidant and detoxifying action. The tool is designed to compensate for the deficiency of ademetionine and activate its production. The drug increases the resistance of liver cells to negative factors, which in turn has a positive effect on the structure of the liver and its functioning.

“Dear, but effective!” - users write in reviews. Indeed, the hepatoprotector is in the top of the most expensive. The course of treatment is usually about 3-4 weeks, during which daily you should take 2-4 tablets twice or three times a day. Thus, the packaging of 20 pieces is enough for a very short period, and to complete the course you have to buy more and more. The expediency of taking the drug can be judged by the results of re-handed tests - they come back to normal.


The best vitamin-like hepatoprotective agents

Supplements as hepatoprotectors - not the most common phenomenon. Such drugs, as a rule, do not guarantee the onset of the expected therapeutic effect. However, some drugs still managed to recommend themselves as quite effective.

2 Ovesol


Choleretic effect. Filter bags
A country: Russia
Average price: 168 rub.
Rating (2019): 4.7

Carefully clean the liver of toxins promises drug "Ovesol." In pharmacies, dietary supplements are presented in the form of tablets, solution and filter bags. It is tea that is particularly popular due to the choleretic herbs added to the brand composition. The manufacturer emphasizes - we face 100% natural remedy: oats, volodushka, rosemary, rosehip, peppermint. Specially selected herbal ingredients have detoxification, anti-inflammatory, analgesic and restorative properties.

Reviews confirm that the tool works. At the end of the course (20 days), you can notice an improvement in appetite and normalization of the digestive system as a whole, the absence of pain in the liver and bitter mouth, getting rid of facial rash, etc. taste without bitterness. Tea in filter bags is recognized by users as an effective measure for the prevention and correction of minor violations of the liver. It is recommended to repeat the course 3-4 times a year.


1 Hepatrine


Detoxification. Sachets
A country: Russia
Average price: 519 rub.
Rating (2019): 4.8

"Hepatrine" is a unique complex of B vitamins and amino acids at an attractive price. L-Ornithine, Inositol and Taurine, which are part of the detox drink, provide for the removal of toxins from hepatocytes, the natural restoration of liver function and the protection of the organ from obesity. The drug does not contain GMOs, gluten and sugar. BAA has a hepatoprotective and detoxification effect. The main advantages of the product are the dosage, frequency and duration of the course, namely, only 1 sachet bag a day after meals for 10 days.

In the reviews mention the pleasant taste of the drink and soon get rid of the feeling of heaviness after eating. A good bonus is reducing acne and leveling the tone of the face. For those who for some reason are inconvenient to take a detox drink, for example, the fact that the powder is very fine, and is very dusty when pouring into a glass, the manufacturer has an alternative - a means in capsules.

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Attention! The above information is not a guide to your purchase. For any advice should contact the experts!

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2 comment
  1. Elizabeth
    For some reason, little is written about Esslial Forte, and this is a domestic drug of good quality. I now increasingly hear about him from the doctors, well, I myself take a prescription. Very effective and competent hepatoprotector.
  2. Svetlana
    I tried many different phospholipids. Now I'm drinking a monthly course of Vitoteca fofsfolipid. I liked that they are with milk thistle extract and B vitamins. With them, I get better and better absorbed. I am satisfied and my body too. I feel good. When I came to the pharmacy I chose honestly by the appearance of the package (I don’t seem to save on it either) + of course, I looked for an alternative to the foreign one from the iherb site (there’s only 400 r for delivery of the same capsules), why If in our pharmacies there is a good composition of 400 mg in 1 capsule.

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